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Bird flu update.......
General Boards - COVID
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Replies: 3
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Bird flu update.......


Dec 27, 2024, 2:23 PM
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We've passed the 7th inning stretch it seems.

https://www.yahoo.com/news/bird-flu-virus-shows-mutations-233012441.html


https://www.yahoo.com/news/bird-flu-mutated-inside-us-174706659.html
As expected, but actually not hoped for, the cow/bird flu is a nothingburger, so far. It is a mild flu humans are readily adapted to fight. It would be better, by a MILE, if the cow flu did adapt to humans, because that would be a mild flu pandemic. Of more danger and concern is flu that infects humans directly from bird sources. The bird->human infections have been generally more severe, although more rare. BUT the dangerous pandemic will come from birds, possibly with swine as an intermediary host. Watch the pigs. If the virus doesn't jump from birds/poultry to humans directly, it will likely be pigs who would be the preferred intermediary.

A teenager in BC got the flu and there was no known cow or poultry/bird contact (couple of months ago). It was very severe, kid spent weeks in ICU on a vent, and now they're not saying anything about him. His flu genome was released, and it's a new one. Kid was infected by a bird, not from a cow or poultry. Likely a wild bird variety.

Now there is another case in Louisiana that is severe. The genome for that patient has also been released. SAME VARIANT as the BC teenager. In both BC and Louisiana cases, they noticed adaptations to better transmit in humans. Multiple genomes from each patient have been released, and it appears that within the human host (BC and Louisiana) the virus is adapting inside THAT ONE PERSON, to better infect humans. This is a very BAD sign, because what will likely happen is this variant will infect more and more people, and as it learns and evolves inside the host, one day it will hit on mutations that pass it to others. This is a step in the wrong direction, and this is a severe strain. It's called D1.1, and its from birds, not cattle. Cattle have the B3.13 strain. If/when person to person transmission happens, it will not take long to work out the final kinks for a pandemic to explode. Weeks, maybe a month. Once passing among people, it will evolve quickly to a pandemic.

And I expect a similar thing occurred with covid, again thinking it was a lab leak. Imperfect virus infects some people, doesn't transmit easily, but within enough hosts it evolves and explodes in Wuhan. Took only 3-4 months, tops.

Bird flu is passing to humans from cows, and from birds directly. Each cases raises the bar a bit higher. If pigs get it, we will almost assuredly get it. Even without pigs, it can still happen.

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Hopefully, when it hits, we'll be able to roll out....


Dec 30, 2024, 8:55 AM
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some quick testing. That was one of the failures during the early months of Covid, not having quick tests that could be rolled out to the general population.

There's also a bird flu vaccine that's been developed. It doesn't have approval yet, but this could be quickly sent out if needed.

https://www.nbcnews.com/health/health-news/two-possible-bird-flu-vaccines-available-weeks-needed-rcna149961

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Full details of the Canadian teenager.


Jan 2, 2025, 10:18 AM
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Horrible. Seems to be all better now, except for the renal failure. Hope that clears up. ECMO and a vent are the most dire things they can do do keep you alive. If this becomes a pandemic I expect most people would never get this level of care. Interesting influenza is behaving like covid, mutating within the infected host.

https://www.nejm.org/doi/full/10.1056/NEJMc2415890

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And the dude in Louisiana is now dead....


Jan 6, 2025, 7:02 PM
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https://www.cnn.com/2025/01/06/health/bird-flu-death-louisiana/index.html

This guy was over 65 with some health issues. But still, very sad, and the first dead American from this thing.

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